by Usha Govindarajulu | Apr 23, 2025 | Biostatistics, Blog, Usha Govindarajulu
April 23, 2025 The authors have discussed a sample size calculation for restricted mean survival time (RMST) in augmented tests. The RMST was developed as an alternative measure of survival that is non-parametric and does not reply on parametric constraints. It had...
by Usha Govindarajulu | Dec 4, 2024 | Biostatistics, Blog, Usha Govindarajulu
December 4, 2024 In restricted mean survival time (RMST) analyses, tau is set at some fixed point or as stated as this paper, treated as a nonrandom, prespecified quantity, sometimes derived from the observed data (Tian, 2020). They developed tau-inflated beta...
by Usha Govindarajulu | Aug 15, 2024 | Blog
August 15, 2024 In clinical trials that use time to event endpoints, a traditional measure has been using the hazard ratio derived from a Cox proportional hazard regression, but one must satisfy this assumption. Over time, measures that have relaxed this assumption...
by Usha Govindarajulu | Jul 17, 2024 | Biostatistics, Blog, Usha Govindarajulu
July 17, 2024 The authors have written a new article about using average hazard (AH) as compared to restricted mean survival time (RMST) as a measure instead of hazard ratios which are instantaneous measures of effect generally obtained through estimation of a Cox...
by Usha Govindarajulu | May 22, 2024 | Biostatistics, Blog, Usha Govindarajulu
May 22, 2024 The authors have presented a review of current survival methods and contemporary methods that could help handle some of the issues that arise with current methods. The authors then went through description of current methods. They discussed censoring and...
