by Usha Govindarajulu | Sep 27, 2023 | Biostatistics, Blog, Usha Govindarajulu
September 25, 2023 The authors, Hanke et al, discussed variable selction methods for linear regression and that the best subset selection (BSS) is not always the best choice. After Bertsimas et al (2016) pushed BSS as a mixed-integer optimization problem (MIO) so...
by Usha Govindarajulu | Sep 14, 2023 | Biostatistics, Usha Govindarajulu
September 13, 2023 In their paper, the authors, Wang et al focused on estimation of casual effects of a treatment on survival outcomes with censoring with propensity score (PS) adjustment. They also used alternative measures of survival like restricted average causal...
by Usha Govindarajulu | Aug 30, 2023 | Biostatistics, Blog, Usha Govindarajulu
August 30, 2023 In this article that appeared in a special issue in the Biometrical Journal, Chen et al describe how restricted mean survival time (RMST), an alternative representation of survival time, can be adapted to have clustering. They were motivated by...
by Usha Govindarajulu | Aug 16, 2023 | Biostatistics, Blog, COVID-19, Epidemiology, Healtcare, Usha Govindarajulu
The authors developed a proportional incidence model to estimate vaccine effectiveness (VE) but at the population level. Understanding VE during the COVID-19 pandemic was very important. Since obtaining individual level data linkages, the authors used aggregated...
by Usha Govindarajulu | Aug 2, 2023 | Biostatistics, Blog, Usha Govindarajulu
August 2, 2023 In this article published in June online, Lancker et al describe a way for valid inference of hazard ratios from a Cox regression after variable selection. The problem has been that it is unknown which amount of covariates to use to control for...
by Usha Govindarajulu | Jul 19, 2023 | Biostatistics, Usha Govindarajulu
Statistical issues in survival analysis (Part XI) July 19, 2023 The authors, Ning et al, have proposed what they refer to as a “broad class” of “so called” Cox-Aalen transformation models which have elements of both multiplicative and additive covariate effects...
