Issues in COVID-19 research and statistical analyses (Part XIV)
Booster shots for all vaccines September 30, 2021 The Centers for Disease Control and Prevention (CDC) has been promoting booster shots most recently for all vaccines for COVID-19: Pfizer, Moderna, and Johnson & Johnson. However, the Food & Druge...
Issues in COVID-19 research and statistical analyses (Part XIII)
J&J Booster shots A more recent controversy has come up with the Johnson & Johnson (J&J) vaccine perhaps needing a booster shot sooner than the mRNA based vaccines for COVID-19. A current problem is there is no verifiable data or rather limited...
Issues in COVID-19 research and statistical analyses (Part XII)
A lot of controversy has come up with the boosters for the COVID-19 vaccines and efficacy. The Israeli study on efficacy comparing people vaccinated last year to people vaccinated this year seemed to indicate the efficacy was waning over time.
Issues in COVID-19 research and statistical analyses (Part XI)
Recently, there has been a lot of news about COVID-19 research tied to the studies conducted in Israel since they have such a high rate of vaccination and since they themselves have conducted several analyses which are very timely for understanding the changes in efficacy of the vaccines, mainly of the Pfizer and Moderna mRNA ones.
Issues in COVID-19 research and statistical analyses (Part X)
As we have heard or know, COVID-19 research, especially in early 2020, was filled with observational studies, many of which were potentially underpowered, but it turns out, even randomized controlled trials. Sample size estimation went out the window. Even Lee...
Issues in COVID-19 research and statistical analyses (Part IX)
With all the news about vaccine efficacy and how long the effects of the vaccine will last, it is interesting to wonder how the statistical models to detect such effects are designed for such research . In the Khoury et al paper (2020), they do consider the decay of...
Issues in COVID-19 research and statistical analyses (Part VIII)
These vaccine rates are being re-updated and re-analyzed, but not very much is discussed about how these rates are constantly analyzed and assessed.
Issues in COVID-19 research and statistical analyses (Part VII)
During the times of uncertainty in statistical methods used in COVID-19 research. Were Bayesian methods employed much in these contexts?
Issues in COVID-19 research and statistical analysis (Part VI)
P-values and vaccine efficacy As the companies continue to re-evaluate vaccine efficacy against new variants, have they discussed p-values? Are they analyzing re-updated data again and again and correcting for inflation of the Type I error rate?? Given the...
Issues in COVID-19 research and statistical analyses (Part V)
COVID-19 challenges of publishing statistically relevant studies COVID-19 is a tricky period in which to attempt to publish new studies. Criticism came from reviewers and those reading the articles whether or not one showed negative results or positive results from...