by Usha Govindarajulu | Sep 23, 2026 | Biostatistics, Blog, Usha Govindarajulu
Statistical issues in survival analysis (NPH hetero covs) September 23, 2026 Currently there is no unified framework for incorporating heterogeneously time-varying effects of covariates. Such effects occur when a covariate affects survival not only in a heterogeneous...
by Usha Govindarajulu | Sep 10, 2026 | Biostatistics, Blog, Usha Govindarajulu
September 10, 2026 The authors proposed use of an outcome-adaptive Lasso (OAL) Cox proportional hazards model as a novel variable selection framework causal inference for right censored data in light of a critical limitation in survival analysis where...
by Usha Govindarajulu | Aug 27, 2026 | Artificial Intelligence, Biostatistics, Blog, Machine Learning, Professor, Usha Govindarajulu
August 26, 2026 In their article, Lang et al (2026) discuss the issues of assessing quality in preclinical research statistically in the age of the emerging use of artificial intelligence (AI). They aimed to show how large language models (LLMs) and more generally...
by Usha Govindarajulu | Aug 12, 2026 | Biostatistics, Blog, Machine Learning, Professor, Usha Govindarajulu
August 12, 2026 The authors, Qiang et al (2026) proposed a semiparametric modeling framework for interval-censored data using a deep generalized accelerated hazards model (DGAHM) which uses Cox proportional hazard regression or accelerated failure time (AFT)...
by Usha Govindarajulu | Jul 29, 2026 | Biostatistics, Blog, Machine Learning, Professor, Usha Govindarajulu
July 29, 2026 The authors published this second article as a two part series about exploring novel approaches to predicting survival outcomes and evaluating model performance. They also provide R code to help in the implementations of these. They then go through and...
by Usha Govindarajulu | Jul 15, 2026 | Biostatistics, Blog, Usha Govindarajulu
July 15, 2026 In the literature, there has been conflicting guidance about when to use multiple testing correction or adjustment. Also, the distinction between a confirmatory vs an exploratory analyses can make all the difference. The guidance has usually been that it...
