by Usha Govindarajulu | Sep 15, 2021 | Biostatistics, Blog, Healtcare, Usha Govindarajulu
J&J Booster shots A more recent controversy has come up with the Johnson & Johnson (J&J) vaccine perhaps needing a booster shot sooner than the mRNA based vaccines for COVID-19. A current problem is there is no verifiable data or rather limited...
by Usha Govindarajulu | Sep 1, 2021 | Biostatistics, Blog, Epidemiology, Healtcare, Usha Govindarajulu
Waning of efficacy and interpretation A lot of controversy has come up with the boosters for the COVID-19 vaccines and efficacy. The Israeli study on efficacy comparing people vaccinated last year to people vaccinated this year seemed to indicate the efficacy...
by Usha Govindarajulu | Aug 18, 2021 | Blog, Epidemiology, Healtcare, Usha Govindarajulu
Understanding percentages and efficacy August 18, 2021 Recently, there has been a lot of news about COVID-19 research tied to the studies conducted in Israel since they have such a high rate of vaccination and since they themselves have conducted several analyses...
by Usha Govindarajulu | Aug 4, 2021 | Biostatistics, Blog, Usha Govindarajulu
As we have heard or know, COVID-19 research, especially in early 2020, was filled with observational studies, many of which were potentially underpowered, but it turns out, even randomized controlled trials. Sample size estimation went out the window. Even Lee...
by Usha Govindarajulu | Jul 21, 2021 | Biostatistics, Blog, Healtcare, Professor, Usha Govindarajulu
With all the news about vaccine efficacy and how long the effects of the vaccine will last, it is interesting to wonder how the statistical models to detect such effects are designed for such research . In the Khoury et al paper (2020), they do consider the decay of...
by Usha Govindarajulu | Jul 9, 2021 | Biostatistics, Blog, Epidemiology, Healtcare, Professor, Usha Govindarajulu
Re-analyses on vaccine efficacy in COVID-19 research Much of the news these days focuses on vaccine efficacy rates being re-updated due to various new COVID-19 variants coming out often, originating in different countries, like delta (B.1.167.2) from India and lambda...
