by Usha Govindarajulu | Oct 24, 2024 | Biostatistics, Blog, Usha Govindarajulu
October 23, 2024 In terms of the Cox proportional hazards model, adding in a lasso feature for variable selection or other penalized method was typically done in the partial likelihood. Their method has sought to add the lasso penalty into the full likelihood. As the...
by Usha Govindarajulu | Aug 15, 2024 | Blog
August 15, 2024 In clinical trials that use time to event endpoints, a traditional measure has been using the hazard ratio derived from a Cox proportional hazard regression, but one must satisfy this assumption. Over time, measures that have relaxed this assumption...
by Usha Govindarajulu | Jul 17, 2024 | Biostatistics, Blog, Usha Govindarajulu
July 17, 2024 The authors have written a new article about using average hazard (AH) as compared to restricted mean survival time (RMST) as a measure instead of hazard ratios which are instantaneous measures of effect generally obtained through estimation of a Cox...
by Usha Govindarajulu | Jul 3, 2024 | Biostatistics, Blog, Usha Govindarajulu
July 4, 2024 The authors discussed the use of the standardized mortality ratio (SMR) to compare survival across centers, especially in the context of U.S. kidney transplant center evaluation. The SMR is calculated based on indirect standardization methods in general...
by Usha Govindarajulu | May 22, 2024 | Biostatistics, Blog, Usha Govindarajulu
May 22, 2024 The authors have presented a review of current survival methods and contemporary methods that could help handle some of the issues that arise with current methods. The authors then went through description of current methods. They discussed censoring and...
