by Usha Govindarajulu | Nov 11, 2023 | Biostatistics, Blog
November 9, 2023 In this article that appeared in a special issue in the Biometrical Journal, Morelle et al described a joint modeling approach to account for the longitudinal followup of patients at subsequent hospitalization or competing risk. While most prognostic...
by Usha Govindarajulu | Oct 25, 2023 | Biostatistics, Blog, Usha Govindarajulu
October 15, 2023 The authors discussed how to handle model joint survival and longitudinal modeling in the presence of informative censoring caused by informative dropouts by participants in a study. The authors framed this in terms of palliative care studies where...
by Usha Govindarajulu | Oct 11, 2023 | Biostatistics, Blog, Usha Govindarajulu
October 11, 2023 In this recent article by Hoogland et al, the authors have proposed combining flexible parametric survival modeling with regularization in order to improve risk prediction modeling for time-to-event data and, thus, they made a unified regularation...
by Usha Govindarajulu | Sep 27, 2023 | Biostatistics, Blog, Usha Govindarajulu
September 25, 2023 The authors, Hanke et al, discussed variable selction methods for linear regression and that the best subset selection (BSS) is not always the best choice. After Bertsimas et al (2016) pushed BSS as a mixed-integer optimization problem (MIO) so...
by Usha Govindarajulu | Aug 30, 2023 | Biostatistics, Blog, Usha Govindarajulu
August 30, 2023 In this article that appeared in a special issue in the Biometrical Journal, Chen et al describe how restricted mean survival time (RMST), an alternative representation of survival time, can be adapted to have clustering. They were motivated by...
by Usha Govindarajulu | Aug 16, 2023 | Biostatistics, Blog, COVID-19, Epidemiology, Healtcare, Usha Govindarajulu
The authors developed a proportional incidence model to estimate vaccine effectiveness (VE) but at the population level. Understanding VE during the COVID-19 pandemic was very important. Since obtaining individual level data linkages, the authors used aggregated...