by Usha Govindarajulu | Aug 15, 2024 | Blog
August 15, 2024 In clinical trials that use time to event endpoints, a traditional measure has been using the hazard ratio derived from a Cox proportional hazard regression, but one must satisfy this assumption. Over time, measures that have relaxed this assumption...
by Usha Govindarajulu | Jul 17, 2024 | Biostatistics, Blog, Usha Govindarajulu
July 17, 2024 The authors have written a new article about using average hazard (AH) as compared to restricted mean survival time (RMST) as a measure instead of hazard ratios which are instantaneous measures of effect generally obtained through estimation of a Cox...
by Usha Govindarajulu | May 22, 2024 | Biostatistics, Blog, Usha Govindarajulu
May 22, 2024 The authors have presented a review of current survival methods and contemporary methods that could help handle some of the issues that arise with current methods. The authors then went through description of current methods. They discussed censoring and...
by Usha Govindarajulu | Mar 13, 2024 | Biostatistics, Blog, Usha Govindarajulu
March 13, 2024 New immunotherapies for cancer have shown to have different treatment effects often with delay compared to other cytotoxic treatments and, therefore, this has called for different ways of modeling the survival curves. The usual log-rank test has relied...
by Usha Govindarajulu | Sep 14, 2023 | Biostatistics, Usha Govindarajulu
September 13, 2023 In their paper, the authors, Wang et al focused on estimation of casual effects of a treatment on survival outcomes with censoring with propensity score (PS) adjustment. They also used alternative measures of survival like restricted average causal...